Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 4/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815604 | 0.78 | MEN1 (0.45) | CYP2C19MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9815632 | 0.74 | CYP3A4 (0.54) | CYP3A4CYP1A2CYP2D6PMP22BLM | |
| SCHEMBL25453163 | 0.72 | CYP1A2 (0.70) | CYP3A4CYP1A2CYP2D6STAT3PMP22 | |
| SCHEMBL9160606 | 0.69 | CYP3A4 (0.57) | CYP3A4CYP1A2CYP2D6STAT3PMP22 | |
| SCHEMBL4878047 | 0.69 | APP (0.62) | CYP3A4CYP1A2CYP2D6PMP22BLM | |
| SCHEMBL4878055 | 0.69 | APP (0.62) | CYP3A4CYP1A2CYP2D6PMP22BLM | |
| SCHEMBL29406655 | 0.69 | AKR1B1 (0.74) | CYP3A4CYP1A2CYP2D6STAT3PMP22 | |
| SCHEMBL10684886 | 0.69 | CYP3A4 (0.64) | CYP3A4CYP1A2CYP2D6STAT3PMP22 | |
| SCHEMBL7522722 | 0.68 | ABL1 (0.51) | CYP3A4CYP1A2CYP2D6STAT3PMP22 | |
| SCHEMBL9828817 | 0.68 | CYP1A2 (0.62) | CYP3A4CYP1A2CYP2D6STAT3PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | disclosed |