SCHEMBL9815686

SCHEMBL9815686

CCCOCc1ccc([O])cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
PTPN6 P29350 1/20 0.36
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ALDH1A1 P00352 2/20 0.33
ESR1 P03372 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
KDR P35968 1/20 0.33
PLA2G4B P0C869 1/20 0.33
LMNA P02545 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648284 0.89 TSHR (0.43) PTPN2PTPN1PTPN6TSHRTDP1
SCHEMBL9815662 0.82 TSHR (0.39) TSHRTDP1L3MBTL1ALDH1A1CA1
SCHEMBL5599359 0.82 NAAA (0.42) PTPN2PTPN1PTPN6TSHRTDP1
SCHEMBL7838626 0.80 AGXT (0.52) TSHRLMNACA1CA2
SCHEMBL863050 0.80 LTA4H (0.48) TSHRTDP1ALDH1A1ESR1CHRM1
SCHEMBL23267781 0.78 TP53 (0.37) PTPN2PTPN1PTPN6TSHRTDP1
SCHEMBL2267112 0.78 TSHR (0.36) PTPN2PTPN1PTPN6TSHRTDP1
SCHEMBL8418497 0.78 IDO1 (0.50) LMNA
SCHEMBL21306509 0.78 CYP3A4 (0.50)
SCHEMBL13799442 0.78 TSHR (0.42) TSHRTDP1L3MBTL1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0120463-B1 ANTHRAQUINONE DYES AND LIQUID CRYSTAL COMPOSITIONS INCLUDING THE SAME HITACHI, LTD. (JP) 1991-11-06 EP disclosed
US-4610804-A Anthraquinone dyes and liquid crystal compositions including the same HITACHI, LTD. (JP) 1986-09-09 US disclosed
EP-0120463-A2 Anthraquinone dyes and liquid crystal compositions including the same HITACHI, LTD. (JP) 1984-10-03 EP disclosed