Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056287 | 0.91 | CES2 (0.62) | ALDH1A1KDM4EMAPTHPGDCES2 | |
| SCHEMBL16926001 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTHPGDCES2 | |
| SCHEMBL10685379 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTHPGDCES2 | |
| SCHEMBL8564034 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTHPGDCES2 | |
| SCHEMBL10425816 | 0.86 | MAOB (0.56) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL6937356 | 0.85 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAPTHPGDCES2 | |
| SCHEMBL10683513 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHPGDCES2 | |
| SCHEMBL10683509 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHPGDCES2 | |
| SCHEMBL22551371 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTHPGDCES2 | |
| SCHEMBL22551372 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTHPGDCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248590-B1 | 1,1,4,4-TETRAPHENYL-1,3- BUTADIENE DERIVATIVES AND ELECTROPHOTOGRAPHIC LIGHTSENSITIVE MATERIAL CONTAINING THEM | Takasago Perfumery Co., Ltd. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4751163-A | CHARGE TRANSPORT LAYER; ELECTROSTATICS; DURABILITY, PERFORMANCE | TAKASAGO PERFUMERY CO., LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0248590-A1 | 1,1,4,4-Tetraphenyl-1,3- butadiene derivatives and electrophotographic lightsensitive material containing them | Takasago Perfumery Co., Ltd. (JP) | 1987-12-09 | — | — | EP | disclosed |