SCHEMBL6937356

SCHEMBL6937356

CC=C(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
KDM4E B2RXH2 2/20 0.65
MAPT P10636 2/20 0.65
HPGD P15428 2/20 0.65
CES2 O00748 2/20 0.56
CES1 P23141 2/20 0.56
CA1 P00915 5/20 0.55
CA2 P00918 5/20 0.55
CA12 O43570 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
PDE4A P27815 2/20 0.53
PDE4B Q07343 2/20 0.53
PDE4C Q08493 2/20 0.53
PDE4D Q08499 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
NR1I2 O75469 1/20 0.52
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL5700298 0.98 ALDH1A1 (0.63) ALDH1A1KDM4EMAPTHPGDCES2
SCHEMBL10473228 0.86 MAOB (0.56) ALDH1A1KDM4EMAPTHPGDCES2
SCHEMBL10473229 0.86 MAOB (0.56) ALDH1A1KDM4EMAPTHPGDCES2
SCHEMBL9815845 0.85 ALDH1A1 (0.65) ALDH1A1KDM4EMAPTHPGDCES2
SCHEMBL8270539 0.84 PDE4A (0.78) ALDH1A1CA1CA2CA12CA7
SCHEMBL23259346 0.83 ALDH1A1 (0.63) ALDH1A1KDM4EMAPTHPGDCES2
SCHEMBL8271268 0.81 ALDH1A1 (0.61) ALDH1A1KDM4EMAPTHPGDCES2
SCHEMBL8994712 0.81 MAPT (0.61) ALDH1A1KDM4EMAPTHPGDCES2
SCHEMBL10683509 0.81 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTHPGDCES2
SCHEMBL10683513 0.81 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTHPGDCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10330603-B1 Mass produced, low cost, portable test kit for the detection and identification of chemical and biological agents VERITEQUE USA, INC. 2019-06-25 US claimed
US-11329229-B2 Hole transporting organic molecules containing enamine groups for optoelectronic and photoelectrochemical devices KAUNO TECHNOLOGIES UNIVERSITETAS (LT) 2022-05-10 US disclosed
US-11225480-B2 Malic enzyme inhibitors SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) 2022-01-18 US disclosed
US-20210115038-A1 MALIC ENZYME INHIBITORS SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) 2021-04-22 US disclosed
US-10330603-B1 Mass produced, low cost, portable test kit for the detection and identification of chemical and biological agents VERITEQUE USA, INC. 2019-06-25 US disclosed
WO-2018051278-A2 HOLE TRANSPORTING ORGANIC MOLECULES CONTAINING ENAMINE GROUPS FOR OPTOELECTRONIC AND PHOTOELECTROCHEMICAL DEVICES Kauno technologijos universitetas (LT) 2018-03-22 WO disclosed
US-20170213652-A1 NOVEL SYNTHONS FOR DEVELOPING ORGANIC SEMICONDUCTORS UNIVERSITÉ DE TOURS (FR) 2017-07-27 US disclosed
US-20170213652-A1 NOVEL SYNTHONS FOR DEVELOPING ORGANIC SEMICONDUCTORS UNIVERSITÉ DE TOURS (FR) 2017-07-27 US disclosed
WO-2016016221-A1 NOVEL SYNTHONS FOR DEVELOPING ORGANIC SEMICONDUCTORS UNIVERSITE DE TOURS FRANCOIS-RABELAIS (FR) 2016-02-04 WO disclosed
US-7262294-B2 Photochromatic pyrano-1,3-oxazinonaphthalene derivatives GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2007-08-28 US disclosed
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 EP disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed
US-4770973-A READABLE BY OPTICAL DEVICES AND FIXED BY LIGHT Kanzaki Paper Manufacturing Limited (JP) 1988-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 ALDH1A1 2369/4885KDM4E 381/4885MAPT 4856/4885
US-20210115038-A1 MALIC ENZYME INHIBITORS ME1, ME2, ME3 ALDH1A1 144/4885KDM4E 1301/4885MAPT 2817/4885
US-11225480-B2 Malic enzyme inhibitors ME1, RNASE1, ME2 ALDH1A1 89/4885KDM4E 821/4885MAPT 3825/4885
US-11329229-B2 Hole transporting organic molecules containing enamine groups for optoelectronic and photoelectrochemical devices OCIAD1, OCIAD2, SLCO4C1 ALDH1A1 594/4885KDM4E 4217/4885MAPT 1504/4885
US-20170213652-A1 NOVEL SYNTHONS FOR DEVELOPING ORGANIC SEMICONDUCTORS NES, NCL, CDK6 ALDH1A1 4288/4885KDM4E 3992/4885MAPT 2048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.