SCHEMBL9815892

SCHEMBL9815892

C=CCn1cnc2cc(Cl)c(Cl)cc21.C=CCn1cnc2cc(Cl)ccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.42
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
PRPS1 P60891 3/20 0.41
FGFR1 P11362 1/20 0.41
LMNA P02545 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
PKM P14618 1/20 0.40
MAPT P10636 1/20 0.39
HSD17B10 Q99714 1/20 0.39
BRD4 O60885 3/20 0.39
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TBXA2R P21731 2/20 0.38
EP300 Q09472 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539099 0.93 FGFR1 (0.46) KCNH2NPC1RAB9APRPS1FGFR1
SCHEMBL4672057 0.90 PRPS1 (0.47) KCNH2NPC1RAB9APRPS1LMNA
SCHEMBL10891175 0.78 PRPS1 (0.44) KCNH2NPC1RAB9APRPS1LMNA
SCHEMBL623907 0.78 MAPT (0.64) NPC1RAB9AFGFR1ALDH1A1KDM4E
SCHEMBL6128998 0.77 POLB (0.43) KCNH2NPC1RAB9AFGFR1LMNA
SCHEMBL8350050 0.76 PRPS1 (0.37) KCNH2NPC1RAB9APRPS1LMNA
SCHEMBL9482398 0.76 NPC1 (0.51) KCNH2NPC1RAB9APRPS1LMNA
SCHEMBL9679438 0.75 ALDH1A1 (0.40) KCNH2PRPS1LMNAALDH1A1KDM4E
SCHEMBL3298971 0.75 PRPS1 (0.37) KCNH2NPC1RAB9APRPS1LMNA
SCHEMBL4673008 0.75 ALDH1A1 (0.40) KCNH2PRPS1LMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0123983-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP disclosed