SCHEMBL3298971

SCHEMBL3298971

C=CCn1cnc2cc(C(F)(F)F)c(Cl)cc21

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRPS1 P60891 4/20 0.37
SCD O00767 1/20 0.34
NOTUM Q6P988 3/20 0.34
KCNH2 Q12809 1/20 0.33
MAPT P10636 1/20 0.33
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
AR P10275 1/20 0.31
TBXA2R P21731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8350050 0.87 PRPS1 (0.37) PRPS1KCNH2MAPTALDH1A1NPC1
SCHEMBL4672057 0.84 PRPS1 (0.47) PRPS1KCNH2MAPTALDH1A1NPC1
SCHEMBL5085211 0.82 NPC1 (0.43) NOTUMKCNH2MAPTALDH1A1NPC1
SCHEMBL6128998 0.77 POLB (0.43) KCNH2MAPTALDH1A1NPC1RAB9A
SCHEMBL10891175 0.75 PRPS1 (0.44) PRPS1KCNH2ALDH1A1NPC1RAB9A
SCHEMBL9815892 0.75 KCNH2 (0.42) PRPS1KCNH2MAPTALDH1A1NPC1
SCHEMBL4673008 0.75 ALDH1A1 (0.40) PRPS1KCNH2ALDH1A1KDM4ELMNA
SCHEMBL9771569 0.75 KDM4E (0.41) ALDH1A1NPC1RAB9AKDM4ELMNA
SCHEMBL10896310 0.74 PRPS1 (0.45) PRPS1ALDH1A1KDM4ETBXA2R
SCHEMBL4681375 0.74 NPSR1 (0.44) MAPTALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741017-B2 Silver halide color photographic light-sensitive material and image formation method using the same, silver halide emulsion, reducing compound having group adsorptive to silver halide and method for producing the same FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
CN-100520574-C Silver halide photosensitive material FUJI PHOTO FILM CO LTD (JP) 2009-07-29 CN disclosed
US-20080242860-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND IMAGE FORMATION METHOD USING THE SAME, SILVER HALIDE EMULSION, REDUCING COMPOUND HAVING GROUP ADSORPTIVE TO SILVER HALIDE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
CN-101124516-A Pattern forming material, pattern forming apparatus, and pattern forming method FUJI FILM CORP (JP) 2008-02-13 CN disclosed
US-7186500-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-06 US disclosed
US-6924091-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-08-02 US disclosed
US-20040175662-A1 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. 2004-09-09 US disclosed
US-20040126720-A1 Silver halide color photographic light-sensitive material and image formation method using the same, silver halide emulsion, reducing compound having group adsorptive to silver halide and method for producing the same FUJI PHOTO FILM CO., LTD. 2004-07-01 US disclosed
US-6756177-B2 MULTICOLOR RECORDING FUJI PHOTO FILM CO., LTD. (JP) 2004-06-29 US disclosed
EP-0314104-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-05-03 EP disclosed
US-4814265-A CONTAINING METHANE DYE FUJI PHOTO FILM CO., LTD. (JP) 1989-03-21 US disclosed
US-4800154-A SPECTRAL SENSITIZINY CYANINE, MEROCYANINE, STYRYL AND OXONOL DYES FUJI PHOTO FILM CO., LTD. (JP) 1989-01-24 US disclosed
US-4740455-A Heat developable light-sensitive material containing polymethine FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed
US-4731793-A METHINE DYES FUJI PHOTO FILM CO., LTD. (JP) 1988-03-15 US disclosed
US-4725532-A CONTAINING HYDRAZIDE DERIVATIVE, CATIONIC DYE AND ASCORBIC ACID FUJI PHOTO FILM CO., LTD. (JP) 1988-02-16 US disclosed
US-4690883-A SENSITIZING DYES; CYANINE AND MEROCYANINE TYPE FUJI PHOTO FILM CO., LTD. (JP) 1987-09-01 US disclosed
US-4596767-A Supersensitizing silver halide photographic material by incorporating therein an infrared sensitizing dye and an imino containing heterocyclic ring compound FUJI PHOTO FILM CO., LTD. (JP) 1986-06-24 US disclosed
US-4581329-A ANTIFOGGING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1986-04-08 US disclosed
EP-0123983-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242860-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND IMAGE FORMATION METHOD USING THE SAME, SILVER HALIDE EMULSION, REDUCING COMPOUND HAVING GROUP ADSORPTIVE TO SILVER HALIDE AND METHOD FOR PRODUCING THE SAME IK, APOL1, CLTA PRPS1 4816/4885SCD 3743/4885NOTUM 3492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.