Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10196775 | 0.96 | HRH3 (0.66) | MAPTHRH3LMNACYP1A2CYP2D6 | |
| SCHEMBL10963711 | 0.90 | LMNA (0.65) | MAPTHRH3LMNACYP1A2CYP2D6 | |
| SCHEMBL8791883 | 0.84 | HRH3 (0.63) | MAPTHRH3LMNACYP1A2CYP2D6 | |
| SCHEMBL3604079 | 0.84 | HRH3 (0.66) | MAPTHRH3LMNACYP1A2CYP2D6 | |
| SCHEMBL10969675 | 0.84 | LMNA (0.69) | MAPTHRH3LMNACYP1A2CYP2D6 | |
| Bromide SCHEMBL8100697 | 0.83 | HRH3 (0.62) | MAPTHRH3LMNACYP1A2CYP2D6 | |
| Bromide SCHEMBL8110043 | 0.82 | HRH3 (0.63) | MAPTHRH3LMNACYP1A2CYP2D6 | |
| SCHEMBL7306800 | 0.81 | HRH3 (0.62) | MAPTHRH3LMNACYP1A2CYP2D6 | |
| SCHEMBL10967350 | 0.81 | LMNA (0.60) | MAPTHRH3LMNACYP1A2CYP2D6 | |
| SCHEMBL9815929 | 0.80 | MAPT (0.97) | MAPTHRH3LMNACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160416-B1 | SUBSTITUTED PYRIDAZINES | Chisso Corporation (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4657695-A | FERROELECTRIC LIQUIDS CRYSTALS | CHISSO CORPORATION (JP) | 1987-04-14 | — | — | US | disclosed |
| EP-0160416-A2 | Substituted pyridazines | Chisso Corporation (JP) | 1985-11-06 | — | — | EP | disclosed |