Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.34 |
| ▸ | MEN1 | O00255 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28246060 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2GAAKMT2AMEN1 | |
| SCHEMBL11555510 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2GAAAKR1B1KMT2A | |
| SCHEMBL28638704 | 0.76 | GABRA1 (0.43) | GABRA1GABRB2GAAMAPTALDH1A1 | |
| SCHEMBL14321847 | 0.76 | GABRA1 (0.44) | GABRA1GABRB2GAAAKR1B1KMT2A | |
| SCHEMBL3646580 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2GAAAKR1B1KMT2A | |
| SCHEMBL7775721 | 0.75 | GABRA1 (0.42) | GABRA1GABRB2GAAAKR1B1KMT2A | |
| SCHEMBL3806685 | 0.75 | GABRA1 (0.42) | GABRA1GABRB2GAAAKR1B1KMT2A | |
| SCHEMBL8969560 | 0.75 | ALDH1A1 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL8156871 | 0.74 | CYP3A4 (0.42) | GABRA1GABRB2GAAKMT2AMEN1 | |
| SCHEMBL3257656 | 0.73 | GABRA1 (0.41) | GABRA1GABRB2GAAAKR1B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3130255-A | — | — | None | — | — | JP | disclosed |
| JP-H03130255-A | ANILINE DERIVATIVE AND ANTI-INFLAMMATORY DRUG CONTAINING THE SAME DERIVATIVE AS ACTIVE INGREDIENT | KIRIN BREWERY CO LTD | 1991-06-04 | — | — | JP | disclosed |
| US-4163659-A | HERBICIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1979-08-07 | — | — | US | disclosed |
| US-4076519-A | N-substituted perfluoroalkanesulfonamides as herbicides | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-3890340-A | Preparation of 2,1-benzisothiazoles | CHEVRON RESEARCH COMPANY, SAN FRANCISCO, CA. A CORP. OF DE. | 1975-06-17 | — | — | US | disclosed |