Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638704 | 0.81 | GABRA1 (0.43) | ALDH1A1TSHRAURKA | |
| SCHEMBL12883976 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRKMT2AAURKAAURKB | |
| SCHEMBL9816019 | 0.75 | GABRA1 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL93414 | 0.72 | CYP3A4 (0.48) | ALDH1A1TSHR | |
| SCHEMBL29648904 | 0.72 | CYP3A4 (0.48) | ALDH1A1TSHR | |
| SCHEMBL9636666 | 0.71 | LMNA (0.48) | ALDH1A1TSHRKMT2A | |
| SCHEMBL15761177 | 0.68 | GABRA1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL150237 | 0.68 | TSHR (0.50) | ALDH1A1TSHRKMT2AAURKAAURKB | |
| SCHEMBL29350459 | 0.68 | TSHR (0.50) | ALDH1A1TSHRKMT2AAURKAAURKB | |
| SCHEMBL11559449 | 0.67 | GAA (0.54) | ALDH1A1TSHRKMT2AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |