Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816351 | 1.00 | LMNA (0.51) | LMNASMN1; SMN2CA2CA1FOLH1 | |
| SCHEMBL11695253 | 0.91 | LMNA (0.44) | LMNASMN1; SMN2CA2CA1FOLH1 | |
| SCHEMBL11695242 | 0.91 | LMNA (0.44) | LMNASMN1; SMN2CA2CA1FOLH1 | |
| SCHEMBL9816280 | 0.81 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9816296 | 0.81 | ALDH1A1 (0.53) | LMNASMN1; SMN2CA2CA1FOLH1 | |
| SCHEMBL9816330 | 0.80 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2CA2CA1ALDH1A1 | |
| SCHEMBL11694441 | 0.80 | LMNA (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL11694445 | 0.80 | LMNA (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL10879046 | 0.79 | LMNA (0.46) | LMNASMN1; SMN2CA2CA1 | |
| SCHEMBL9816278 | 0.79 | LMNA (0.46) | LMNASMN1; SMN2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153992-B1 | WATER SOLUBLE DERIVATIVES OF 3,5-DIACETO AMIDO-2,4,6-TRIIODOBENZOIC ACID AND PROCESS FOR THEIR PREPARATION AND USE | Dr. Franz Köhler Chemie GmbH (DE) | 1991-10-16 | — | — | EP | claimed |
| EP-0153992-B1 | WATER SOLUBLE DERIVATIVES OF 3,5-DIACETO AMIDO-2,4,6-TRIIODOBENZOIC ACID AND PROCESS FOR THEIR PREPARATION AND USE | Dr. Franz Köhler Chemie GmbH (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-4607123-A | X-RAY CONTRAST AGENTS | DR. FRANZ KOHLER CHEMIE GMBH (DE) | 1986-08-19 | — | — | US | disclosed |
| EP-0153992-A2 | Water soluble derivatives of 3,5-diaceto amido-2,4,6-triiodobenzoic acid and process for their preparation and use | Dr. Franz Köhler Chemie GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |