Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | FPR2 | P25090 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRN | P28799 | 3/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816330 | 0.86 | SMN1; SMN2 (0.49) | ALDH1A1FPR2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL10879046 | 0.84 | LMNA (0.46) | LMNAGRNSORT1SMN1; SMN2CA2 | |
| SCHEMBL9816278 | 0.84 | LMNA (0.46) | LMNAGRNSORT1SMN1; SMN2CA2 | |
| SCHEMBL9816290 | 0.84 | PPID (0.43) | ALDH1A1FPR2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11012483 | 0.82 | FOLH1 (0.49) | LMNAFOLH1SMN1; SMN2 | |
| SCHEMBL9816288 | 0.82 | ITGB2 (0.49) | ALDH1A1FPR2LMNAMEN1KMT2A | |
| SCHEMBL9816279 | 0.82 | ITGB2 (0.49) | ALDH1A1FPR2LMNAMEN1KMT2A | |
| SCHEMBL9816351 | 0.81 | LMNA (0.51) | ALDH1A1FPR2LMNAFOLH1SMN1; SMN2 | |
| SCHEMBL9816331 | 0.81 | LMNA (0.51) | ALDH1A1FPR2LMNAFOLH1SMN1; SMN2 | |
| SCHEMBL11012485 | 0.80 | CA2 (0.43) | LMNAKMT2AFOLH1SMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153992-B1 | WATER SOLUBLE DERIVATIVES OF 3,5-DIACETO AMIDO-2,4,6-TRIIODOBENZOIC ACID AND PROCESS FOR THEIR PREPARATION AND USE | Dr. Franz Köhler Chemie GmbH (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-4607123-A | X-RAY CONTRAST AGENTS | DR. FRANZ KOHLER CHEMIE GMBH (DE) | 1986-08-19 | — | — | US | disclosed |
| EP-0153992-A2 | Water soluble derivatives of 3,5-diaceto amido-2,4,6-triiodobenzoic acid and process for their preparation and use | Dr. Franz Köhler Chemie GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |