Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19142344 | 0.88 | TP53 (0.61) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4633890 | 0.87 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL27453980 | 0.84 | CA1 (0.48) | CA1CA2CA7CA9CA12 | |
| SCHEMBL28621325 | 0.82 | CA1 (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11508229 | 0.82 | CA1 (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11420633 | 0.82 | CA1 (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL19808 | 0.82 | INPPL1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11740601 | 0.82 | CA1 (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4633888 | 0.82 | CA1 (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL30770359 | 0.82 | INPPL1 (0.57) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021054927-A2 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2021-03-25 | — | — | WO | claimed |
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2020-02-13 | — | — | US | claimed |
| US-9622969-B2 | Polymer conjugated protein micelles | SOUTH DAKOTA STATE UNIV (US) | 2017-04-18 | — | — | US | claimed |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | SOUTH DAKOTA STATE UNIVERSITY (US) | 2014-12-18 | — | — | US | claimed |
| EP-2729136-A1 | DRUG COMBINATIONS AND USES IN TREATING A COUGHING CONDITION | Biocopea Limited (GB) | 2014-05-14 | — | — | EP | claimed |
| CN-103648488-A | Pharmaceutical compositions and use in treating cough conditions | BIOCOPEA LTD | 2014-03-19 | — | — | CN | claimed |
| EP-2608847-A1 | THEOBROMINE IN COMBINATION WITH AN EXPECTORANT OR A MUCOLYTIC FOR USE IN THERAPY | Biocopea Limited (GB) | 2013-07-03 | — | — | EP | claimed |
| CN-103189108-A | Theobromine in combination with an expectorant or a mucolytic for use in therapy | BIOCOPEA LTD | 2013-07-03 | — | — | CN | claimed |
| WO-2013004999-A1 | DRUG COMBINATIONS AND USES IN TREATING A COUGHING CONDITION | BIOCOPEA LIMITED (GB) | 2013-01-10 | — | — | WO | claimed |
| WO-2012025761-A1 | THEOBROMINE IN COMBINATION WITH AN EXPECTORANT OR A MUCOLYTIC FOR USE IN THERAPY | BIOCOPEA LIMITED (GB) | 2012-03-01 | — | — | WO | claimed |
| EP-2214716-B1 | HYDROXYAPATITE-TARGETING MULTIARM POLYMERS AND CONJUGATES MADE THEREFROM | NEKTAR THERAPEUTICS (US) | 2021-11-17 | — | — | EP | disclosed |
| US-11116789-B2 | Compositions and methods for pain relief without numbness | BDA-12, LLC | 2021-09-14 | — | — | US | disclosed |
| CN-108291123-B | Cellulose acetate wood filler composition | 醋酸纤维国际有限责任公司 | 2021-04-23 | — | — | CN | disclosed |
| WO-2021064059-A1 | NON-METALLIC PHOSPHORUS ANTIWEAR ADDITIVES | CASTROL LIMITED (GB) | 2021-04-08 | — | — | WO | disclosed |
| WO-2021064059-A1 | NON-METALLIC PHOSPHORUS ANTIWEAR ADDITIVES | CASTROL LIMITED (GB) | 2021-04-08 | — | — | WO | disclosed |
| US-5261903-A | Composite anesthetic article and method of use | M.D. INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-5226901-A | Buffering systems; adding sodium bicarbonate | M.D., INC. | 1993-07-13 | — | — | US | disclosed |
| US-5209724-A | Buffering local anesthetic, reducing pain and irritation on injection | M.D., INC. | 1993-05-11 | — | — | US | disclosed |
| US-5149320-A | Using parenteral solution containing sodium bicarbonate and dissolved carbon dioxide | M.D., INC. | 1992-09-22 | — | — | US | disclosed |
| EP-0055313-A1 | Guaiacol and derivatives; compositions thereof and use in a method of treatment | ED. GEISTLICH SÖHNE AG FÜR CHEMISCHE INDUSTRIE (CH) | 1982-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | GSTK1, GSTO1, GSTM2 | CA1 725/4885CA2 2428/4885CA7 2739/4885 |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | MTDH, PSMG3, GHITM | CA1 3087/4885CA2 4462/4885CA7 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.