Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10555368 | 1.00 | SIGMAR1 (0.67) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| Hydrochloric Acid SCHEMBL10562806 | 0.98 | SIGMAR1 (0.65) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| SCHEMBL7120636 | 0.84 | SIGMAR1 (0.61) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| SCHEMBL13452473 | 0.81 | ALDH1A1 (0.57) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| Fenfluramine SCHEMBL29447403 | 0.80 | SLC6A4 (1.00) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| Levofenfluramine SCHEMBL162006 | 0.80 | SLC6A4 (1.00) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| Dexfenfluramine SCHEMBL15669714 | 0.80 | SLC6A4 (1.00) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| Fenfluramine SCHEMBL16215 | 0.80 | SLC6A4 (1.00) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| Levofenfluramine SCHEMBL29882976 | 0.80 | SLC6A4 (1.00) | SIGMAR1SLC6A4LMNAMAPTADRA2C | |
| Dexfenfluramine SCHEMBL16706 | 0.80 | SLC6A4 (1.00) | SIGMAR1SLC6A4LMNAMAPTADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301925-B1 | PROCESS FOR THE ENANTIOSPECIFIC PREPARATION OF (S)2-ETHYL AMINO-1-3-(TRIFLUOROMETHYL PHENYL) PROPANE | ADIR ET COMPAGNIE (FR) | 1991-10-23 | — | — | EP | disclosed |