Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 4/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816894 | 0.84 | SIGMAR1 (0.67) | SIGMAR1SLC6A4TP53TSHRLMNA | |
| SCHEMBL10555368 | 0.84 | SIGMAR1 (0.67) | SIGMAR1SLC6A4TP53TSHRLMNA | |
| Hydrochloric Acid SCHEMBL10562806 | 0.82 | SIGMAR1 (0.65) | SIGMAR1SLC6A4TP53TSHRLMNA | |
| SCHEMBL23986713 | 0.81 | TAAR1 (0.59) | SIGMAR1SLC6A4TP53TSHRACACB | |
| SCHEMBL25530544 | 0.79 | CYP1A2 (0.61) | SIGMAR1SLC6A4TP53TSHRACACB | |
| SCHEMBL25530939 | 0.79 | TP53 (0.53) | SIGMAR1SLC6A4TP53TSHRADRA1A | |
| SCHEMBL19012043 | 0.79 | SIGMAR1 (0.68) | SIGMAR1SLC6A4TSHRLMNAMAPT | |
| SCHEMBL4680337 | 0.77 | SIGMAR1 (0.66) | SIGMAR1SLC6A4TSHRLMNAMAPT | |
| SCHEMBL22249109 | 0.77 | SIGMAR1 (0.66) | SIGMAR1SLC6A4TSHRLMNAMAPT | |
| SCHEMBL8441968 | 0.77 | SIGMAR1 (0.66) | SIGMAR1SLC6A4TSHRHTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178922-C | Substituted 1-aminoalkyllactam compounds and their use as muscarinic receptor antagonists | - | 2004-12-08 | — | — | CN | disclosed |
| US-6667301-B2 | Therapy for muscular disorders, urogenital disorders, gastrointestinal disorders, respiratory system disorders | SYNTEX (U.S.A.) LLC | 2003-12-23 | — | — | US | disclosed |
| CN-1430610-A | Substituted 1-aminoalkyllactam compounds and their use as muscarinic receptor antagonists | HOFFMANN LA ROCHE (CH) | 2003-07-16 | — | — | CN | disclosed |
| US-20020004501-A1 | Heterocyclylalkylamines as muscarinic receptor antagonists | SYNTEX (U.S.A.) LLC | 2002-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004501-A1 | Heterocyclylalkylamines as muscarinic receptor antagonists | CHRM5, CHRM2, CHRM1 | SIGMAR1 32/4885SLC6A4 880/4885TP53 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.