Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817018 | 0.90 | BACE1 (0.42) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL9817023 | 0.87 | BACE1 (0.42) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL1595103 | 0.81 | BACE1 (0.58) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL24639580 | 0.81 | BACE1 (0.48) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL27885449 | 0.80 | BACE1 (0.56) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL7916586 | 0.80 | BACE1 (0.56) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL26388933 | 0.79 | HSD17B1 (0.49) | BACE1ALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL2863692 | 0.78 | BACE1 (0.54) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL22317285 | 0.77 | BACE1 (0.52) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL4282140 | 0.76 | PTPN5 (0.57) | BACE1ALDH1A1HPGDBCL2L1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277627-B1 | POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-10-23 | — | — | EP | disclosed |
| US-4801679-A | Polyformal resin and process for producing said resin | IDEMITSU KOSAN CO., LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0277627-A1 | Polyformal resins and process for producing said resins | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |