SCHEMBL4282140

SCHEMBL4282140

CC(C)c1ccc(O)c(-c2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 1/20 0.57
BACE1 P56817 2/20 0.56
PTGS1 P23219 4/20 0.52
TRPA1 O75762 1/20 0.52
CACNA1C Q13936 1/20 0.52
RXRA P19793 1/20 0.51
NR4A2 P43354 1/20 0.51
ALDH1A1 P00352 3/20 0.50
ALOX12 P18054 2/20 0.50
HTT P42858 2/20 0.50
HIF1A Q16665 2/20 0.50
GAA P10253 1/20 0.50
HPGD P15428 3/20 0.48
BCL2L1 Q07817 1/20 0.48
HSD17B10 Q99714 1/20 0.48
RNASEH1 O60930 1/20 0.47
PELI1 Q96FA3 1/20 0.45
CYP2D6 P10635 1/20 0.44
METAP2 P50579 1/20 0.44
LMNA P02545 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1176815 0.89 BACE1 (0.56) PTPN5BACE1PTGS1RXRANR4A2
SCHEMBL7435559 0.88 TRPA1 (0.55) PTPN5BACE1PTGS1TRPA1CACNA1C
SCHEMBL11951626 0.86 ALOX5 (0.55) PTPN5BACE1PTGS1TRPA1CACNA1C
SCHEMBL21612700 0.85 BACE1 (0.52) PTPN5BACE1PTGS1RXRANR4A2
SCHEMBL1596833 0.84 BACE1 (0.60) PTPN5BACE1PTGS1ALDH1A1ALOX12
SCHEMBL11651790 0.83 TRPA1 (0.64) PTPN5PTGS1TRPA1CACNA1CALDH1A1
SCHEMBL25906319 0.83 TRPA1 (0.55) PTPN5BACE1PTGS1TRPA1CACNA1C
SCHEMBL1595103 0.82 BACE1 (0.58) PTPN5BACE1PTGS1ALDH1A1ALOX12
SCHEMBL11552886 0.82 BACE1 (0.58) PTPN5BACE1PTGS1ALDH1A1ALOX12
SCHEMBL22888737 0.82 ALOX5 (0.53) PTPN5PTGS1TRPA1CACNA1CRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110065804-A1 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2011-03-17 US claimed
WO-2009120784-A2 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2009-10-01 WO claimed
WO-2002050002-A1 NON-HALOGENATED PHENYL SUBSTITUTED PHENOLS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO claimed
CN-119192867-A High-softening-point isotropic asphalt and preparation method and application thereof 湖南碳导新材料科技有限公司 2024-12-27 CN disclosed
CN-113924629-B Conductive paste composition 京都一来电子化学股份有限公司 2024-04-09 CN disclosed
US-11713335-B2 Aminocoumarin compounds and methods of their use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-08-01 US disclosed
CN-115698217-A Phenolic resin composition for friction material 住友电木株式会社 2023-02-03 CN disclosed
WO-2019178119-A1 AMINOCOUMARIN COMPOUNDS AND METHODS OF THEIR USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2019-09-19 WO disclosed
US-20190257049-A1 Methods and Apparatus for Stabilization of Surfaces Polylast Systems, LLC 2019-08-22 US disclosed
US-10309070-B2 Methods and apparatus for stabilization of surfaces Polylast Systems, LLC (US) 2019-06-04 US disclosed
US-9982143-B2 Methods and apparatus for stabilization of surfaces Polylast Systems, LLC (US) 2018-05-29 US disclosed
US-20170002533-A1 Methods and Apparatus for Stabilization of Surfaces KING COAST INC. 2017-01-05 US disclosed
US-20160333192-A1 Methods and Apparatus for Stabilization of Surfaces KING COAST INC. 2016-11-17 US disclosed
US-20110065804-A1 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2011-03-17 US disclosed
WO-2009120784-A2 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2009-10-01 WO disclosed
US-7211700-B2 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same MCNEIL-PPC, INC. (US) 2007-05-01 US disclosed
US-20050239903-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same MCNEIL-PPC, INC 2005-10-27 US disclosed
US-20030207945-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same HARPER DAVID SCOTT (US) 2003-11-06 US disclosed
US-20020119106-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same HARPER DAVID SCOTT (US) 2002-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207945-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same TYR, CLPP, PTPN1 PTPN5 13/4885BACE1 4837/4885PTGS1 2901/4885
US-20050239903-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same TYR, CLPP, PTPN1 PTPN5 13/4885BACE1 4837/4885PTGS1 2901/4885
US-20020119106-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same TYR, CLPP, PTPN1 PTPN5 13/4885BACE1 4837/4885PTGS1 2901/4885
US-11713335-B2 Aminocoumarin compounds and methods of their use AAAS, PROC, AADAC PTPN5 3801/4885BACE1 3953/4885PTGS1 1090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.