Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035379 | 0.87 | SCN1A (0.31) | SMN1; SMN2HTT | |
| SCHEMBL29065683 | 0.83 | TP53 (0.45) | SMN1; SMN2HTTKDM4EALDH1A1NPC1 | |
| SCHEMBL28699366 | 0.83 | TP53 (0.45) | SMN1; SMN2HTTKDM4EALDH1A1NPC1 | |
| SCHEMBL12904575 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2HTTKDM4EALDH1A1RAB9A | |
| SCHEMBL14445313 | 0.79 | TSHR (0.40) | SMN1; SMN2HTTKDM4EALDH1A1NPC1 | |
| SCHEMBL1135115 | 0.79 | CA12 (0.46) | KDM4EALDH1A1TSHRCYP1A2CYP2C19 | |
| SCHEMBL8018068 | 0.76 | — | — | |
| Diethanolamine SCHEMBL1832822 | 0.76 | KDM4E (0.39) | SMN1; SMN2HTTKDM4EALDH1A1NPC1 | |
| Diethanolamine SCHEMBL1833343 | 0.76 | KDM4E (0.39) | SMN1; SMN2HTTKDM4EALDH1A1NPC1 | |
| SCHEMBL15894724 | 0.76 | CHRNB2 (0.39) | SMN1; SMN2HTTKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150011-B1 | CATALYTIC PROCESS FOR THE PREPARATION OF AMIDES | KLÜBER LUBRICATION MÜNCHEN KG (DE) | 1991-10-30 | — | — | EP | disclosed |
| EP-0150011-A2 | Catalytic process for the preparation of amides | KLÜBER LUBRICATION MÜNCHEN KG (DE) | 1985-07-31 | — | — | EP | disclosed |