Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23045236 | 0.91 | LMNA (0.46) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28980314 | 0.87 | CHRM2 (0.38) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28883097 | 0.87 | LMNA (0.39) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18116052 | 0.82 | LMNA (0.41) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1246711 | 0.82 | CA12 (0.46) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL26103979 | 0.81 | SMN1; SMN2 (0.39) | TSHRCHRNB2CHRNA4LMNACYP2C19 | |
| SCHEMBL20094988 | 0.80 | ALOX15 (0.46) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| Diethanolamine SCHEMBL4612680 | 0.80 | ALOX15 (0.65) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9817079 | 0.79 | SMN1; SMN2 (0.41) | TSHRCHRNB2CHRNA4LMNACYP2C19 | |
| SCHEMBL28356069 | 0.78 | LMNA (0.39) | TSHRCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191263-A1 | Valency platform molecules comprising aminooxy groups | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191263-A1 | Valency platform molecules comprising aminooxy groups | DAO, PAM, BCAT2 | TSHR 4451/4885CHRM2 4436/4885CHRM4 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.