Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817289 | 0.85 | AKR1B1 (0.49) | TYRPKMTAAR1AKR1B1 | |
| SCHEMBL9817338 | 0.81 | HPGD (0.41) | NPC1AKR1B1APP | |
| SCHEMBL9275342 | 0.80 | TDP1 (0.64) | NPC1RAB9ATDP1TAAR1APP | |
| SCHEMBL9817264 | 0.77 | GPR35 (0.42) | CYP4F2CYP4A11TDP1IAPP | |
| SCHEMBL9817323 | 0.77 | ALDH1A1 (0.41) | TDP1APP | |
| SCHEMBL1246063 | 0.76 | CYP4F2 (0.76) | CYP4F2CYP4A11TYRNPC1PKM | |
| SCHEMBL14606370 | 0.75 | TDP1 (0.51) | CYP4F2CYP4A11TYRNPC1PKM | |
| SCHEMBL9817275 | 0.74 | TDP1 (0.44) | TYRTDP1TAAR1APP | |
| SCHEMBL14360800 | 0.74 | CYP4F2 (0.58) | CYP4F2CYP4A11TYRNPC1PKM | |
| SCHEMBL28662041 | 0.74 | TDP1 (0.54) | CYP4F2CYP4A11TDP1AKR1B1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248213-B1 | HYDROXYPHENYL- AND HYDROXYPHENOXYALKANOIC ACID IODOPROPARGYL ESTERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4731466-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0248213-A2 | Hydroxyphenyl- and hydroxyphenoxyalkanoic acid iodopropargyl esters | THE DOW CHEMICAL COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |