Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | IAPP | P10997 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817282 | 0.82 | ALDH1A1 (0.41) | GPR35ALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL9445177 | 0.81 | CYP4F2 (0.54) | GPR35ALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL9817277 | 0.77 | CYP4F2 (0.47) | TDP1CYP4F2CYP4A11IAPP | |
| SCHEMBL9817323 | 0.76 | ALDH1A1 (0.41) | GPR35ALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL9817262 | 0.75 | GPR35 (0.41) | GPR35ERN1ALDH1A1MAPTTDP1 | |
| SCHEMBL11312676 | 0.75 | MAOB (0.45) | ALDH1A1MEN1KMT2AHTTHPGD | |
| SCHEMBL9817214 | 0.72 | GPR35 (0.42) | GPR35ALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL1919090 | 0.70 | CYP4F2 (0.63) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL27864868 | 0.70 | GPR35 (0.53) | GPR35ERN1ALDH1A1MAPTTDP1 | |
| SCHEMBL9817275 | 0.69 | TDP1 (0.44) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248213-B1 | HYDROXYPHENYL- AND HYDROXYPHENOXYALKANOIC ACID IODOPROPARGYL ESTERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4731466-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0248213-A2 | Hydroxyphenyl- and hydroxyphenoxyalkanoic acid iodopropargyl esters | THE DOW CHEMICAL COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |