Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635359 | 0.88 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3385712 | 0.85 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7627400 | 0.84 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL11755151 | 0.83 | LMNA (0.67) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31527717 | 0.83 | LMNA (0.67) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8780712 | 0.81 | KMT2A (0.71) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9349824 | 0.80 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9161457 | 0.78 | RAB9A (0.64) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7631521 | 0.78 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2ARECQL | |
| SCHEMBL21128712 | 0.78 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242611-B1 | LONG WAVE UV-RAY ABSORBER | Kao Corporation (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4837010-A | DIBENZOYLMETHANE DERIVATIVE; SUNSCREEN AGENTS | KAO CORPORATION (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0242611-A1 | Long wave UV-ray absorber | Kao Corporation (JP) | 1987-10-28 | — | — | EP | disclosed |