Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627400 | 0.93 | NPC1 (0.72) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL9817316 | 0.88 | NPC1 (0.63) | NPC1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7629094 | 0.86 | MMP1 (0.61) | NPC1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7629413 | 0.86 | L3MBTL1 (0.66) | NPC1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7631521 | 0.86 | NPC1 (0.64) | NPC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL21128712 | 0.86 | NPC1 (0.67) | NPC1MAPTSMN1; SMN2MAPK1KDM4E | |
| SCHEMBL29446640 | 0.86 | MAPT (0.69) | NPC1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL460957 | 0.85 | CES2 (0.63) | NPC1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL845256 | 0.85 | L3MBTL1 (0.77) | NPC1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28912681 | 0.84 | PLK1 (0.72) | NPC1MAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448304-B1 | POLYURETHANE, POLYTHIOURETHANE OR DIETHYLENE GLYCOL BISALLYLCARBONATE POLYMER; DIPPING IN SOLUTION CONTAINING A DIBENZOYLMETHANE OR A BENZOTRIZOLE COMPOUND; PLASTIC LENS FOR SPECTACLES WHICH ABSORBS ULTRAVIOLET RAYS; LOW YELLOWNESS | HOYA CORPORATION (JP) | 2002-09-10 | — | — | US | disclosed |