Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817338 | 0.86 | HPGD (0.41) | KMT2AHIF1AMEN1HPGDCYP3A4 | |
| SCHEMBL9817289 | 0.80 | AKR1B1 (0.49) | KMT2AHIF1AMEN1CYP3A4USP2 | |
| SCHEMBL9817283 | 0.79 | ITGA4 (0.41) | KMT2AMEN1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL10785636 | 0.78 | POLB (0.51) | KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL6076931 | 0.78 | MEN1 (0.57) | KMT2AHIF1AMEN1HPGDCYP3A4 | |
| SCHEMBL10789794 | 0.75 | KMT2A (0.42) | KMT2AUSP2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4034721 | 0.74 | EGFR (0.55) | KMT2AHIF1AMEN1HPGDCYP3A4 | |
| SCHEMBL31306792 | 0.74 | EGFR (0.55) | KMT2AHIF1AMEN1HPGDCYP3A4 | |
| SCHEMBL10785203 | 0.73 | ALDH1A1 (0.38) | KMT2AMEN1HTTCYP2C9CYP2C19 | |
| SCHEMBL11310766 | 0.72 | GAA (0.41) | KMT2AMEN1CYP3A4HTTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248213-B1 | HYDROXYPHENYL- AND HYDROXYPHENOXYALKANOIC ACID IODOPROPARGYL ESTERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4731466-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0248213-A2 | Hydroxyphenyl- and hydroxyphenoxyalkanoic acid iodopropargyl esters | THE DOW CHEMICAL COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |