Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 4/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817323 | 0.88 | ALDH1A1 (0.41) | ITGA4ITGB7CTSBMEN1CRHBP | |
| SCHEMBL9817214 | 0.81 | GPR35 (0.42) | MEN1KMT2AALDH1A1TP53HPGD | |
| SCHEMBL9817337 | 0.81 | PTGDR2 (0.39) | KMT2AALDH1A1TP53HPGDTSHR | |
| SCHEMBL10788795 | 0.80 | LMNA (0.49) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2189271 | 0.80 | EGFR (0.51) | CTSBMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9817397 | 0.79 | KMT2A (0.44) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL10785728 | 0.78 | GPR35 (0.37) | MEN1KMT2AALDH1A1HPGDMAPK1 | |
| SCHEMBL9817289 | 0.76 | AKR1B1 (0.49) | MEN1KMT2AALDH1A1TSHRMAPK1 | |
| SCHEMBL9817305 | 0.75 | YWHAG (0.41) | MEN1KMT2AALDH1A1HPGDGPR35 | |
| SCHEMBL9817280 | 0.74 | ITGA4 (0.40) | ITGA4ITGB7CTSBNOX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248213-B1 | HYDROXYPHENYL- AND HYDROXYPHENOXYALKANOIC ACID IODOPROPARGYL ESTERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4731466-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0248213-A2 | Hydroxyphenyl- and hydroxyphenoxyalkanoic acid iodopropargyl esters | THE DOW CHEMICAL COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |