Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199932 | 0.92 | IGF1R (0.33) | ALDH1A1IGF1RALOX15 | |
| SCHEMBL5544401 | 0.80 | IGF1R (0.53) | ALDH1A1IGF1RALOX15 | |
| SCHEMBL5545863 | 0.75 | IGF1R (0.56) | ALDH1A1IGF1RALOX15 | |
| SCHEMBL5539473 | 0.73 | IGF1R (0.54) | ALDH1A1IGF1RALOX15 | |
| SCHEMBL9818299 | 0.73 | ALDH1A1 (0.39) | ALDH1A1CYP3A4HPGDCRHBPCRHR2 | |
| SCHEMBL3741298 | 0.72 | TAAR1 (0.46) | IGF1RALOX15 | |
| SCHEMBL9026650 | 0.72 | IGF1R (0.36) | ALDH1A1IGF1RALOX15CYP3A4HPGD | |
| SCHEMBL12474302 | 0.71 | ALDH1A1 (0.38) | ALDH1A1IGF1RALOX15CYP3A4HPGD | |
| SCHEMBL28404106 | 0.71 | HPGD (0.48) | ALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL3739458 | 0.71 | SKP2 (0.32) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126635-B1 | NOVEL OXINDOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |
| US-4694017-A | 2-amido 3(oxindol-3-yl)propionic acids having antiulcer activity | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-15 | — | — | US | disclosed |
| EP-0126635-A2 | Novel oxindole derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-28 | — | — | EP | disclosed |