SCHEMBL9818482

SCHEMBL9818482

C=CCNCCC[N+](C)(C)CC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.39
ATM Q13315 1/20 0.39
BBOX1 O75936 6/20 0.37
ALDH1A1 P00352 4/20 0.36
GAA P10253 2/20 0.36
KDM4E B2RXH2 5/20 0.35
LMNA P02545 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MEN1 O00255 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TSHR P16473 1/20 0.33
APEX1 P27695 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13665281 0.77 CBLB (0.43) KMT2AATMBBOX1ALDH1A1LMNA
SCHEMBL19630714 0.77 DNM1 (0.40) KMT2AATMBBOX1
SCHEMBL3958580 0.77 ZDHHC20 (0.50) KMT2AATMBBOX1ALDH1A1GAA
SCHEMBL9556892 0.76 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL6271835 0.75 CBLB (0.34) BBOX1ALDH1A1LMNATSHRAPEX1
Bromide SCHEMBL2270678 0.75 ZDHHC20 (0.49) KMT2AATMBBOX1ALDH1A1GAA
SCHEMBL4782686 0.75 DNM1 (0.43) KMT2AATM
SCHEMBL4931018 0.75 KMT2A (0.34) KMT2AATMBBOX1
SCHEMBL714615 0.74 MEN1 (0.38) KMT2AKDM4ELMNARAB9AMEN1
SCHEMBL4393305 0.74 ABCC4 (0.52) KMT2AATMBBOX1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251250-B1 HAIR TREATING COMPOSITION Henkel Kommanditgesellschaft auf Aktien (DE) 1991-08-28 EP disclosed
US-4784801-A ALKYLETHER SULFONATES FROM CORRESPONDING SULFATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-11-15 US disclosed
EP-0175106-B1 THERMOPLASTIC COMPOSITIONS BASED ON POLYPHENYLENE ETHERS, STYRENE HOMOPOLYMERS AND PULVERIZED RUBBER CONTAINING A FILLER, AND PROCESS FOR PREPARING THEM HÜLS AKTIENGESELLSCHAFT (DE) 1988-07-27 EP disclosed