Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 7/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818606 | 0.87 | SLC1A1 (0.46) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL27398633 | 0.79 | NOS3 (0.30) | NOS1NOS3NOS2 | |
| SCHEMBL10783477 | 0.79 | SLC7A5 (0.41) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL31266856 | 0.78 | ITGB3 (0.35) | — | |
| SCHEMBL4586895 | 0.77 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL28729833 | 0.77 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL1504409 | 0.77 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL10667207 | 0.77 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL9800490 | 0.77 | SLC7A5 (0.48) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL27644223 | 0.76 | SLC7A5 (0.42) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028627-A | Controlling blood pressure during chemotherapy | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-07-02 | — | — | US | disclosed |