Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818668 | 0.87 | CNR1 (0.70) | CNR1SMN1; SMN2TP53LMNAKMT2A | |
| SCHEMBL9818621 | 0.86 | CNR1 (0.66) | MAPTCNR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL300331 | 0.86 | CNR1 (0.72) | CNR1SMN1; SMN2TP53LMNAKMT2A | |
| SCHEMBL9818712 | 0.85 | ALDH1A1 (0.69) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9818698 | 0.82 | MAPT (0.59) | MAPTCNR1RAB9ATP53LMNA | |
| SCHEMBL9818742 | 0.82 | TP53 (0.62) | MAPTCNR1SMN1; SMN2TP53LMNA | |
| SCHEMBL9818726 | 0.82 | TP53 (0.62) | MAPTSMN1; SMN2TP53LMNAKMT2A | |
| SCHEMBL9641050 | 0.81 | TP53 (0.64) | MAPTCNR1SMN1; SMN2TP53LMNA | |
| SCHEMBL9818656 | 0.81 | MAPT (0.65) | MAPTCNR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9640397 | 0.80 | TP53 (0.65) | MAPTCNR1SMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015644-A | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds | WARNER-LAMBERT COMPANY (US) | 1991-05-14 | — | — | US | disclosed |