Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818668 | 0.84 | CNR1 (0.70) | MEN1KMT2ACNR1LMNAALDH1A1 | |
| SCHEMBL300331 | 0.83 | CNR1 (0.72) | MEN1KMT2ACNR1LMNAALDH1A1 | |
| SCHEMBL9818643 | 0.82 | MAPT (0.56) | MAPTMEN1RAB9AKMT2ACNR1 | |
| SCHEMBL9818764 | 0.81 | ALDH1A1 (0.52) | MAPTMEN1KMT2ACNR1TRPV1 | |
| SCHEMBL9818712 | 0.80 | ALDH1A1 (0.69) | MAPTMEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL23447441 | 0.78 | MAPT (0.71) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL9818656 | 0.78 | MAPT (0.65) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL9818576 | 0.76 | LMNA (0.68) | MEN1KMT2ACNR1LMNAALDH1A1 | |
| SCHEMBL9818669 | 0.76 | CNR1 (0.87) | MAPTMEN1RAB9AKMT2AEPHX2 | |
| SCHEMBL9818621 | 0.76 | CNR1 (0.66) | MAPTMEN1RAB9AKMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015644-A | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds | WARNER-LAMBERT COMPANY (US) | 1991-05-14 | — | — | US | disclosed |