SCHEMBL9818754

SCHEMBL9818754

COc1cc(O)c(C=O)cc1C=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
TDP1 Q9NUW8 2/20 0.63
KDM4E B2RXH2 1/20 0.63
TSHR P16473 1/20 0.63
ERN1 O75460 10/20 0.53
TRIM24 O15164 2/20 0.53
TRIM33 Q9UPN9 2/20 0.53
TYR P14679 1/20 0.53
HPGD P15428 2/20 0.50
LMNA P02545 1/20 0.50
TLR2 O60603 1/20 0.48
TLR1 Q15399 1/20 0.48
TLR6 Q9Y2C9 1/20 0.48
AOX1 Q06278 1/20 0.48
ALDH5A1 P51649 1/20 0.48
ABAT P80404 1/20 0.48
PRKDC P78527 1/20 0.47
MAPT P10636 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22635018 0.92 ALDH1A1 (0.69) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL29730976 0.89 ALDH1A1 (0.65) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL333221 0.89 ALDH1A1 (0.65) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL769297 0.89 ALDH1A1 (0.65) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL6234401 0.88 ERN1 (0.53) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL1002368 0.88 ALDH1A1 (0.69) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL29459727 0.88 ALDH1A1 (0.69) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL10849623 0.84 ALDH1A1 (0.86) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL15349701 0.84 ERN1 (0.53) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL3639878 0.84 ERN1 (0.53) ALDH1A1TDP1KDM4ETSHRERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5003091-A Preparation of 3-memory-4,5-methylenedioxybenzaldehyde RHONE-POULENC CHIMIE (FR) 1991-03-26 US disclosed