Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.53 |
| ▸ | ABAT | P80404 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004432 | 0.92 | ALDH1A1 (0.57) | ERN1ALDH1A1TRIM24TRIM33TDP1 | |
| SCHEMBL29459687 | 0.92 | ALDH1A1 (0.57) | ERN1ALDH1A1TRIM24TRIM33TDP1 | |
| SCHEMBL29730976 | 0.89 | ALDH1A1 (0.65) | ERN1ALDH1A1TRIM24TRIM33TDP1 | |
| SCHEMBL333221 | 0.89 | ALDH1A1 (0.65) | ERN1ALDH1A1TRIM24TRIM33TDP1 | |
| SCHEMBL9818754 | 0.88 | ALDH1A1 (0.63) | ERN1ALDH1A1TRIM24TRIM33TDP1 | |
| SCHEMBL22635018 | 0.88 | ALDH1A1 (0.69) | ERN1ALDH1A1TRIM24TRIM33TDP1 | |
| SCHEMBL1002368 | 0.88 | ALDH1A1 (0.69) | ERN1ALDH1A1TRIM24TRIM33TDP1 | |
| SCHEMBL29459727 | 0.88 | ALDH1A1 (0.69) | ERN1ALDH1A1TRIM24TRIM33TDP1 | |
| SCHEMBL5361924 | 0.88 | ALDH1A1 (0.69) | ERN1ALDH1A1TRIM24TRIM33TDP1 | |
| SCHEMBL769297 | 0.85 | ALDH1A1 (0.65) | ERN1ALDH1A1TRIM24TRIM33TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349539-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC SUBSTANCE | ZEON CORPORATION (JP) | 2017-12-07 | — | — | US | disclosed |
| US-9776954-B2 | Polymerizable compound, polymerizable composition, polymer, and optically anisotropic substance | ZEON CORPORATION (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20150274647-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC SUBSTANCE | ZEON CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| WO-2005009384-A2 | EGFR TYROSINE KINASE INHIBITORS | IMCLONE SYSTEMS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |
| US-20040049056-A1 | Process for preparation of esculetin compounds, esculetin compounds and intermediates thereof, and use of both | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1357118-A1 | PROCESS FOR PREPARATION OF ESCULETIN COMPOUNDS, ESCULETIN COMPOUNDS AND INTERMEDIATES THEREOF, AND USE OF BOTH | Kureha Chemical Industry Co., Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-0576974-B1 | Benzyliden-quinuclidinones as sunscreen agents | MERCK PATENT GMBH (DE) | 2003-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049056-A1 | Process for preparation of esculetin compounds, esculetin compounds and intermediates thereof, and use of both | SUCLG1, SALL4, HSD17B14 | ERN1 1019/4885ALDH1A1 71/4885TRIM24 1156/4885 |
| US-20150274647-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC SUBSTANCE | PYM1, CCNB2, CCNT1 | ERN1 2245/4885ALDH1A1 1453/4885TRIM24 552/4885 |
| US-20170349539-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC SUBSTANCE | PYM1, CCNB2, CCNT1 | ERN1 2245/4885ALDH1A1 1453/4885TRIM24 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.