Sugi Predict

Sugi Predict / Compounds / SCHEMBL333221

SCHEMBL333221

SCHEMBL333221

COc1cc(O)c(C=O)cc1OC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.65
▸ KDM4E B2RXH2 2/20 0.65
▸ TDP1 Q9NUW8 2/20 0.65
▸ TSHR P16473 1/20 0.65
▸ PRKDC P78527 2/20 0.59
▸ ERN1 O75460 10/20 0.55
▸ TRIM24 O15164 2/20 0.55
▸ TRIM33 Q9UPN9 2/20 0.55
▸ TYR P14679 1/20 0.55
▸ CYP3A4 P08684 1/20 0.52
▸ MAPT P10636 1/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ HSD17B10 Q99714 1/20 0.52
▸ TLR2 O60603 1/20 0.50
▸ TLR1 Q15399 1/20 0.50
▸ TLR6 Q9Y2C9 1/20 0.50
▸ AOX1 Q06278 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ ALDH5A1 P51649 1/20 0.50
▸ ABAT P80404 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29730976 1.00 ALDH1A1 (0.65) ALDH1A1KDM4ETDP1TSHRPRKDC
SCHEMBL6234401 0.89 ERN1 (0.53) ALDH1A1KDM4ETDP1TSHRPRKDC
SCHEMBL22635018 0.89 ALDH1A1 (0.69) ALDH1A1KDM4ETDP1TSHRPRKDC
SCHEMBL9818754 0.89 ALDH1A1 (0.63) ALDH1A1KDM4ETDP1TSHRPRKDC
SCHEMBL1004432 0.89 ALDH1A1 (0.57) ALDH1A1KDM4ETDP1TSHRPRKDC
SCHEMBL29459687 0.89 ALDH1A1 (0.57) ALDH1A1KDM4ETDP1TSHRPRKDC
SCHEMBL10796564 0.86 ERN1 (0.54) ALDH1A1KDM4ETDP1TSHRPRKDC
SCHEMBL15349701 0.86 ERN1 (0.53) ALDH1A1KDM4ETDP1TSHRPRKDC
SCHEMBL31652446 0.86 ERN1 (0.53) ALDH1A1KDM4ETDP1TSHRPRKDC
SCHEMBL3639878 0.86 ERN1 (0.53) ALDH1A1KDM4ETDP1TSHRPRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926188-A Salphen-based metal organic framework material, and preparation method and application thereof 天津大学 2023-04-07 — — CN claimed
EP-1079821-A4 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2001-08-29 — — EP claimed
EP-1079821-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2001-03-07 — — EP claimed
WO-1999059570-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1999-11-25 — — WO claimed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 — — US claimed
US-20260085188-A1 Specific Benzopyrylium Salts as Dyestuffs for Photopolymer Compositions COVESTRO DEUTSCHLAND AG (DE) 2026-03-26 — — US disclosed
US-12540144-B2 Rapafucin derivative compounds and methods of use thereof THE JOHNS HOPKINS UNIVERSITY (US) 2026-02-03 — — US disclosed
EP-4584335-A1 SPECIFIC BENZOPYRYLIUM SALTS AS DYESTUFFS FOR PHOTOPOLYMER COMPOSITIONS Covestro Deutschland AG (DE) 2025-07-16 — — EP disclosed
US-20240239810-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF THE JOHNS HOPKINS UNIVERSITY 2024-07-18 — — US disclosed
US-11970448-B2 Monomers capable of dimerizing in an aqueous solution, and methods of using same CORNELL UNIVERSITY (US) 2024-04-30 — — US disclosed
US-11945827-B2 Rapafucin derivative compounds and methods of use thereof THE JOHNS HOPKINS UNIVERSITY (US) 2024-04-02 — — US disclosed
WO-2024052256-A1 SPECIFIC BENZOPYRYLIUM SALTS AS DYESTUFFS FOR PHOTOPOLYMER COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2024-03-14 — — WO disclosed
US-4992465-A Antidepressant, anxiolytic agents; treating central nervous system disorders CIBA-GEIGY CORPORATION (US) 1991-02-12 — — US disclosed
US-4952571-A Pyridazinone derivatives AKZO, N.V. (NL) 1990-08-28 — — US disclosed
EP-0343643-A2 Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents WARNER-LAMBERT COMPANY (US) 1989-11-29 — — EP disclosed
US-4801605-A ANTIDEPRESSANT, NERVOUS SYSTEM DISORDERS, SEROTONIC ANTAGONIST CIBA-GEIGY CORPORATION (US) 1989-01-31 — — US disclosed
EP-0280269-A1 3-Amino-dihydro-[1]-benzopyrans and benzothiopyrans CIBA-GEIGY AG (CH) 1988-08-31 — — EP disclosed
US-4600719-A Tetrahydropyridine and piperidine derivatives CIBA GEIGY CORPORATION (US) 1986-07-15 — — US disclosed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 — — US disclosed
US-4210655-A Anti-depressant benzofuranyl piperidines CIBA-GEIGY CORPORATION (US) 1980-07-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970448-B2 Monomers capable of dimerizing in an aqueous solution, and methods of using same CALCOCO2, MDN1, MBNL1 ALDH1A1 4582/4885KDM4E 4611/4885TDP1 2053/4885
US-11945827-B2 Rapafucin derivative compounds and methods of use thereof RICTOR, FKBP14, MTOR ALDH1A1 4678/4885KDM4E 3663/4885TDP1 4591/4885
US-20260085188-A1 Specific Benzopyrylium Salts as Dyestuffs for Photopolymer Compositions HBG1, HBG2, HACL2 ALDH1A1 112/4885KDM4E 1735/4885TDP1 3955/4885
US-12540144-B2 Rapafucin derivative compounds and methods of use thereof RICTOR, CHP1, FKBP8 ALDH1A1 4764/4885KDM4E 4000/4885TDP1 4679/4885
US-20240239810-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF RICTOR, MTOR, FKBP14 ALDH1A1 4631/4885KDM4E 3832/4885TDP1 4518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.