Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389957 | 0.79 | — | — | |
| SCHEMBL18562094 | 0.73 | POLB (0.50) | POLBKMT2ACSNK2A2CSNK2A1CSNK2B | |
| SCHEMBL11393881 | 0.70 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL20115738 | 0.67 | CGAS (0.42) | KMT2ALMNAMAPTHSD17B10 | |
| SCHEMBL19425507 | 0.65 | TYMP (0.59) | POLBKMT2ATYMPALDH1A1TDP1 | |
| SCHEMBL11163087 | 0.65 | KMT2A (0.49) | POLBKMT2ACSNK2A2CSNK2A1CSNK2B | |
| SCHEMBL7987260 | 0.62 | KDM4E (0.37) | POLBKMT2ACSNK2A2CSNK2A1CSNK2B | |
| SCHEMBL9196543 | 0.62 | KMT2A (0.50) | POLBKMT2ACSNK2A2CSNK2A1CSNK2B | |
| Tiazotic Acid SCHEMBL6409061 | 0.61 | POLB (0.51) | POLBKMT2ACSNK2A2CSNK2A1CSNK2B | |
| SCHEMBL11502827 | 0.61 | KMT2A (0.44) | POLBKMT2ACSNK2A2CSNK2A1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213718-B1 | 1-DIMETHYLCARBAMOYL-3-SUBSTITUTED-5-SUBSTITUTED-1H-1,2,4-TRIAZOLES | ROHM AND HAAS COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |