Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828607 | 0.77 | LMNA (0.39) | KDM4EALPLALPIALPGMPI | |
| SCHEMBL11584813 | 0.68 | KMT2A (0.40) | ALPLKMT2APOLBLMNAALDH1A1 | |
| SCHEMBL7814368 | 0.67 | — | — | |
| SCHEMBL11584118 | 0.67 | — | — | |
| SCHEMBL10966224 | 0.66 | ALDH1A1 (0.50) | LMNAALDH1A1MAPTCYP1A2 | |
| SCHEMBL11584539 | 0.66 | SMN1; SMN2 (0.47) | KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL7814460 | 0.65 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL21634159 | 0.63 | SMN1; SMN2 (0.57) | LMNAALDH1A1MAPT | |
| SCHEMBL15332609 | 0.62 | ALDH1A1 (0.50) | KDM4EKMT2APOLBLMNAALDH1A1 | |
| SCHEMBL7971675 | 0.62 | ALDH1A1 (0.57) | POLBLMNAALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014310-A1 | PLEUROMUTILIN β-KETOESTERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | claimed |