Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819158 | 0.86 | SMN1; SMN2 (0.49) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9819208 | 0.86 | TSHR (0.40) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL9819176 | 0.83 | APP (0.46) | ALDH1A1MEN1KMT2AMAPTPTPN22 | |
| SCHEMBL9819188 | 0.81 | DAO (0.38) | MCL1DAOALDH1A1KMT2AGSTO1 | |
| SCHEMBL9819413 | 0.81 | TSHR (0.37) | MCL1ALDH1A1TSHRGLAMEN1 | |
| SCHEMBL9818956 | 0.77 | PIM1 (0.39) | MCL1DAOALDH1A1MEN1KMT2A | |
| SCHEMBL9818966 | 0.72 | MCL1 (0.39) | MCL1ALDH1A1TSHRGLAMEN1 | |
| SCHEMBL9819399 | 0.70 | MAPT (0.37) | ALDH1A1TSHRMAPT | |
| SCHEMBL9819164 | 0.68 | SMN1; SMN2 (0.43) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL9577076 | 0.67 | ALDH1A1 (0.52) | ALDH1A1TSHRGLAGSTO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | claimed |
| US-4918206-A | DIURETICS, HYPOTENSIVE AGENTS; SIDE EFFECT REDUCTION | SHIONOGI & CO., LTD. (JP) | 1990-04-17 | — | — | US | claimed |