Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819205 | 0.85 | TP53 (0.43) | APPTEX264TP53MEN1KMT2A | |
| SCHEMBL9818958 | 0.83 | MCL1 (0.40) | MEN1KMT2APTPN22MAPTALDH1A1 | |
| SCHEMBL9819158 | 0.80 | SMN1; SMN2 (0.49) | TP53MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9819181 | 0.79 | APP (0.48) | APPTEX264TP53MEN1KMT2A | |
| SCHEMBL9819188 | 0.73 | DAO (0.38) | APPKMT2AALDH1A1 | |
| SCHEMBL11712969 | 0.72 | KMT2A (0.71) | APPTEX264TP53MEN1KMT2A | |
| SCHEMBL9819208 | 0.71 | TSHR (0.40) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14367385 | 0.67 | APP (0.51) | APPTEX264TP53MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9040981 | 0.66 | CNR2 (0.47) | APPTEX264TP53MEN1KMT2A | |
| SCHEMBL9819413 | 0.66 | TSHR (0.37) | MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | claimed |
| US-4918206-A | DIURETICS, HYPOTENSIVE AGENTS; SIDE EFFECT REDUCTION | SHIONOGI & CO., LTD. (JP) | 1990-04-17 | — | — | US | claimed |
| EP-0312338-A1 | Sulfamoyl-2-benzofurancarboxylic acid derivatives, their preparation and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1989-04-19 | — | — | EP | claimed |