Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819118 | 0.86 | ALDH1A1 (0.33) | SMN1; SMN2KMT2ATSHRLMNAMEN1 | |
| SCHEMBL9819076 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL9819164 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL11670492 | 0.65 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL9819158 | 0.63 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL5237128 | 0.60 | MAPT (0.37) | KMT2ATSHRCYP2C19LMNAKDM4E | |
| SCHEMBL4716499 | 0.60 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL11688661 | 0.59 | MCOLN3 (0.47) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL6241755 | 0.59 | ADORA3 (0.55) | KMT2ACYP1A2CYP2C19MEN1POLB | |
| SCHEMBL11597649 | 0.59 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2ATSHRCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | claimed |