Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29831793 | 0.91 | THRB (0.61) | THRBTHRATSHRALDH1A1TP53 | |
| SCHEMBL27715829 | 0.89 | THRB (0.57) | THRBTHRATSHRALDH1A1TP53 | |
| SCHEMBL27368628 | 0.89 | THRB (0.63) | THRBTHRATSHRALDH1A1TP53 | |
| SCHEMBL7189818 | 0.88 | ALOX5 (0.61) | THRBTHRATSHRALDH1A1TP53 | |
| SCHEMBL7138671 | 0.85 | THRB (0.50) | THRBTHRATSHRALDH1A1TP53 | |
| SCHEMBL29376736 | 0.85 | THRB (0.50) | THRBTHRATSHRALDH1A1TP53 | |
| SCHEMBL28241610 | 0.85 | THRB (0.54) | THRBTHRATSHRALDH1A1TP53 | |
| SCHEMBL9634566 | 0.85 | THRB (0.50) | THRBTHRATSHRALDH1A1TP53 | |
| SCHEMBL3390967 | 0.85 | THRB (0.56) | THRBTHRATSHRALDH1A1TP53 | |
| SCHEMBL28458289 | 0.84 | THRB (0.49) | THRBTHRATSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217205-B1 | COPOLYMERISABLE PHOTOINITIATORS | CIBA-GEIGY AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| EP-0217205-A2 | Copolymerisable photoinitiators | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |