Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376736 | 1.00 | THRB (0.50) | THRBTHRAALOX5TSHRALDH1A1 | |
| SCHEMBL9634566 | 0.91 | THRB (0.50) | THRBTHRAALOX5TSHRALDH1A1 | |
| SCHEMBL9819115 | 0.85 | THRB (0.55) | THRBTHRAALOX5TSHRALDH1A1 | |
| SCHEMBL27368628 | 0.84 | THRB (0.63) | THRBTHRAALOX5TSHRALDH1A1 | |
| SCHEMBL7189818 | 0.82 | ALOX5 (0.61) | THRBTHRAALOX5TSHRALDH1A1 | |
| SCHEMBL28241610 | 0.80 | THRB (0.54) | THRBTHRAALOX5TSHRALDH1A1 | |
| SCHEMBL3390967 | 0.80 | THRB (0.56) | THRBTHRAALOX5TSHRALDH1A1 | |
| SCHEMBL29831793 | 0.80 | THRB (0.61) | THRBTHRAALOX5TSHRALDH1A1 | |
| SCHEMBL7859948 | 0.79 | THRB (0.55) | THRBTHRAALOX5TSHRALDH1A1 | |
| SCHEMBL145662 | 0.79 | THRB (0.55) | THRBTHRATSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377026-B2 | Dental adhesive material kit | KURARAY NORITAKE DENTAL INC. (JP) | 2025-08-05 | — | — | US | claimed |
| US-6512068-B1 | Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of | KURARAY CO., LTD. (JP) | 2003-01-28 | — | — | US | claimed |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | KURARAY NORITAKE DENTAL INC. (JP) | 2026-05-12 | — | — | US | disclosed |
| EP-4725470-A1 | CURABLE DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2026-04-15 | — | — | EP | disclosed |
| US-12527725-B2 | Solvent-free dental adhesive composition | KURARAY NORITAKE DENTAL INC. (JP) | 2026-01-20 | — | — | US | disclosed |
| EP-4649938-A1 | DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2025-11-19 | — | — | EP | disclosed |
| US-12377026-B2 | Dental adhesive material kit | KURARAY NORITAKE DENTAL INC. (JP) | 2025-08-05 | — | — | US | disclosed |
| US-20250213433-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | KURARAY NORITAKE DENTAL INC. (JP) | 2025-07-03 | — | — | US | disclosed |
| US-20250186309-A1 | DENTAL CURABLE COMPOSITION AND DENTAL KIT | KURARAY NORITAKE DENTAL INC. (JP) | 2025-06-12 | — | — | US | disclosed |
| US-20250064687-A1 | DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER | KURARAY NORITAKE DENTAL INC. (JP) | 2025-02-27 | — | — | US | disclosed |
| EP-4505993-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | Kuraray Noritake Dental Inc. (JP) | 2025-02-12 | — | — | EP | disclosed |
| US-20210007938-A1 | LOW WATER-SENSITIVE DENTAL COMPOSITION | SHOFU INC. (JP) | 2021-01-14 | — | — | US | disclosed |
| EP-3733151-A1 | LOW-WATER-SENSITIVE DENTAL COMPOSITION | Shofu Inc. (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-3566689-A2 | DENTAL ADHESIVE COMPOSITION INCLUDING CHAIN TRANSFER AGENT | Shofu Inc. (JP) | 2019-11-13 | — | — | EP | disclosed |
| US-10149802-B2 | Filler characterized by acidic polymer treatment method | SHOFU INC. (JP) | 2018-12-11 | — | — | US | disclosed |
| US-20160213576-A1 | FILLER CHARACTERIZED BY ACIDIC POLYMER TREATMENT METHOD | SHOFU INC. (JP) | 2016-07-28 | — | — | US | disclosed |
| US-6512068-B1 | Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of | KURARAY CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| US-5122061-A | Two part composition of acrylate or methacrylate monomers, trialkylboron or oxide thereof; for dental composite resin | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| EP-0282280-B1 | CURABLE ADHESIVE COMPOSITIONS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0282280-A1 | Curable adhesive compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10149802-B2 | Filler characterized by acidic polymer treatment method | HDAC10, H1-10, CACNA1G | THRB 2760/4885THRA 612/4885ALOX5 2287/4885 |
| US-20250213433-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | CDH1, MACF1, ICAM1 | THRB 3873/4885THRA 2732/4885ALOX5 667/4885 |
| US-12527725-B2 | Solvent-free dental adhesive composition | CDH1, ITGA1, ITGB8 | THRB 2741/4885THRA 2020/4885ALOX5 155/4885 |
| US-20210007938-A1 | LOW WATER-SENSITIVE DENTAL COMPOSITION | MGMT, DNMT3A, TAS2R1 | THRB 2752/4885THRA 1318/4885ALOX5 1908/4885 |
| US-20250064687-A1 | DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER | MGMT, SEM1, CARM1 | THRB 2375/4885THRA 1620/4885ALOX5 2325/4885 |
| US-20250186309-A1 | DENTAL CURABLE COMPOSITION AND DENTAL KIT | KIT, DNMT3L, CDK6 | THRB 2727/4885THRA 2160/4885ALOX5 3598/4885 |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | MSL1, ITGA1, ITGAL | THRB 2959/4885THRA 1194/4885ALOX5 1891/4885 |
| US-20160213576-A1 | FILLER CHARACTERIZED BY ACIDIC POLYMER TREATMENT METHOD | HDAC10, H1-10, CACNA1G | THRB 2760/4885THRA 612/4885ALOX5 2287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.