Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818959 | 0.84 | MAPT (0.62) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL14192526 | 0.83 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL14862701 | 0.82 | LMNA (0.60) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL30168150 | 0.82 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL10674588 | 0.82 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL14202810 | 0.82 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL11144382 | 0.80 | KMT2A (0.70) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL11184067 | 0.80 | GAA (0.54) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL2072200 | 0.80 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL4490833 | 0.79 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |