Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174795 | 0.85 | THRB (0.56) | THRBTSHRHPGDALDH1A1KDM4E | |
| SCHEMBL14574017 | 0.84 | THRB (0.61) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL8034175 | 0.84 | THRB (0.57) | THRBTSHRHPGDALDH1A1KDM4E | |
| SCHEMBL3880984 | 0.83 | THRB (0.60) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL9819178 | 0.83 | THRB (0.42) | THRBTSHRALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL196997 | 0.81 | THRB (0.57) | THRBTSHRHPGDALDH1A1KDM4E | |
| SCHEMBL9819166 | 0.79 | CYP3A4 (0.45) | THRBALDH1A1LMNAGAATHRA | |
| SCHEMBL14173110 | 0.79 | THRB (0.65) | THRBTSHRHPGDALDH1A1KDM4E | |
| SCHEMBL9819130 | 0.79 | CYP3A4 (0.50) | THRBTSHRALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL12039352 | 0.79 | THRB (0.65) | THRBTSHRHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217205-B1 | COPOLYMERISABLE PHOTOINITIATORS | CIBA-GEIGY AG (CH) | 1991-12-11 | — | — | EP | disclosed |