Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819166 | 0.84 | CYP3A4 (0.45) | THRBCTSKALDH1A1CYP3A4MEN1 | |
| SCHEMBL9819130 | 0.84 | CYP3A4 (0.50) | THRBCTSKALDH1A1CYP3A4TSHR | |
| SCHEMBL9819239 | 0.83 | THRB (0.53) | THRBALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL9819162 | 0.82 | THRB (0.39) | THRBALDH1A1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL9819229 | 0.79 | THRB (0.58) | THRBALDH1A1MEN1KMT2ATHRA | |
| Estragole SCHEMBL28079195 | 0.76 | ALDH1A1 (0.63) | THRBALDH1A1ALOX15TP53CYP3A4 | |
| SCHEMBL16740537 | 0.75 | ALDH1A1 (0.47) | THRBCTSKALDH1A1ALOX15TP53 | |
| SCHEMBL9819123 | 0.72 | THRB (0.56) | THRBALDH1A1CYP3A4KMT2AL3MBTL1 | |
| SCHEMBL28523295 | 0.72 | THRB (0.60) | THRBALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL24733310 | 0.72 | ALDH1A1 (0.46) | CTSKALDH1A1ALOX15TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217205-B1 | COPOLYMERISABLE PHOTOINITIATORS | CIBA-GEIGY AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| EP-0217205-A2 | Copolymerisable photoinitiators | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |