Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819162 | 0.86 | THRB (0.39) | CYP3A4CYP2C19CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL9819130 | 0.85 | CYP3A4 (0.50) | CYP3A4CYP2C19CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL9819178 | 0.84 | THRB (0.42) | CYP3A4LMNACTSKTHRBTHRA | |
| SCHEMBL9819229 | 0.80 | THRB (0.58) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL9819239 | 0.79 | THRB (0.53) | LMNATHRBTHRAPPARGPPARA | |
| SCHEMBL8161806 | 0.72 | THRA (0.47) | CYP3A4CYP2C19CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL10603222 | 0.72 | MIF (0.39) | CYP3A4CYP2C19CYP1A2CYP2D6LMNA | |
| SCHEMBL2852281 | 0.70 | PPARA (0.42) | CYP3A4CYP2C19CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL5344254 | 0.70 | PPARA (0.51) | CYP3A4CYP2C19CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL5514535 | 0.70 | TSHR (0.34) | CYP3A4THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217205-B1 | COPOLYMERISABLE PHOTOINITIATORS | CIBA-GEIGY AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| EP-0217205-A2 | Copolymerisable photoinitiators | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |