Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819417 | 0.90 | KIF11 (0.50) | MEN1KMT2AGPR17RXFP1MAPT | |
| SCHEMBL9818946 | 0.87 | ABCG2 (0.50) | MEN1KMT2ARXFP1MAPTABCG2 | |
| SCHEMBL9818865 | 0.87 | ABCG2 (0.50) | MEN1KMT2ARXFP1MAPTABCG2 | |
| SCHEMBL9819230 | 0.86 | IDO1 (0.52) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL9818991 | 0.83 | IDO1 (0.49) | MEN1KMT2ARXFP1MAPTLMNA | |
| SCHEMBL9818928 | 0.81 | EPHX2 (0.50) | NPC1RAB9AIDO1TRPV1 | |
| SCHEMBL9818885 | 0.80 | MEN1 (0.46) | MEN1KMT2AGPR17MAPTGAA | |
| SCHEMBL31546618 | 0.80 | KMT2A (0.79) | MEN1KMT2AGPR17RXFP1MAPT | |
| SCHEMBL9818871 | 0.78 | AR (0.59) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9819219 | 0.78 | AR (0.48) | MEN1KMT2AMAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |