Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 4/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819804 | 0.86 | CTSK (0.33) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL9819787 | 0.80 | REN (0.45) | CTSKCTSLCTSBMETAP2REN | |
| Hydrochloric Acid SCHEMBL9514901 | 0.75 | CTSK (0.38) | CTSKCTSLCTSBCTSHCTSS | |
| Hydrochloric Acid SCHEMBL9514897 | 0.75 | CTSK (0.38) | CTSKCTSLCTSBCTSHCTSS | |
| Hydrochloric Acid SCHEMBL7838394 | 0.65 | METAP1 (0.41) | CTSKCTSSMETAP2METAP1CPB2 | |
| SCHEMBL19269480 | 0.65 | CYP1A2 (0.38) | CTSKMETAP2METAP1 | |
| SCHEMBL3806162 | 0.65 | METAP2 (0.44) | CTSKCTSLCTSBCTSHMETAP2 | |
| SCHEMBL702586 | 0.65 | METAP2 (0.44) | CTSKCTSLCTSBCTSHMETAP2 | |
| SCHEMBL702585 | 0.65 | METAP2 (0.44) | CTSKCTSLCTSBCTSHMETAP2 | |
| SCHEMBL240252 | 0.65 | METAP2 (0.44) | CTSKCTSLCTSBCTSHMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4935405-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4814342-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | disclosed |