Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28128649 | 0.81 | CHRM3 (0.70) | SIGMAR1CHRM3FAAH | |
| SCHEMBL9484550 | 0.81 | OPRK1 (0.67) | OPRK1SIGMAR1CHRM3FAAHHRH2 | |
| SCHEMBL9484534 | 0.81 | OPRK1 (0.67) | OPRK1SIGMAR1CHRM3FAAHHRH2 | |
| SCHEMBL27564901 | 0.80 | SIGMAR1 (0.73) | SIGMAR1CHRM3FAAH | |
| SCHEMBL13149981 | 0.78 | CHRM3 (0.65) | OPRK1SIGMAR1CHRM3FAAH | |
| SCHEMBL27597094 | 0.78 | SIGMAR1 (0.70) | SIGMAR1CHRM3FAAH | |
| SCHEMBL27945272 | 0.77 | OPRK1 (0.59) | OPRK1SIGMAR1HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL7982333 | 0.77 | SIGMAR1 (0.97) | SIGMAR1FAAH | |
| SCHEMBL15961276 | 0.76 | SIGMAR1 (0.91) | SIGMAR1FAAH | |
| SCHEMBL2962629 | 0.76 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |