SCHEMBL2962629

SCHEMBL2962629

c1ccc(CCCN2CCN(CCCc3ccccc3)CC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 1.00
CCR3 P51677 1/20 0.75
POLB P06746 1/20 0.75
LTA4H P09960 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6550825 1.00 SIGMAR1 (1.00) SIGMAR1CCR3POLBLTA4H
SCHEMBL3593088 0.92 SIGMAR1 (0.89) SIGMAR1CCR3POLBLTA4H
SCHEMBL11801794 0.92 CCR3 (0.89) SIGMAR1CCR3
SCHEMBL8092982 0.91 SIGMAR1 (0.85) SIGMAR1CCR3
SCHEMBL5302082 0.91 LTA4H (0.86) SIGMAR1CCR3POLBLTA4H
SCHEMBL3633616 0.90 SIGMAR1 (0.81) SIGMAR1CCR3POLBLTA4H
SCHEMBL11399131 0.90 SIGMAR1 (0.81) SIGMAR1CCR3POLBLTA4H
SCHEMBL7329630 0.90 SIGMAR1 (0.81) SIGMAR1CCR3POLBLTA4H
SCHEMBL14824971 0.90 SIGMAR1 (0.81) SIGMAR1CCR3POLBLTA4H
SCHEMBL83687 0.90 SIGMAR1 (0.86) SIGMAR1CCR3POLBLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4129392-A1 FAST-DISSOLVING MICRONEEDLE Cosmed Pharmaceutical Co., Ltd. (JP) 2023-02-08 EP disclosed
CN-115397401-A Adhesive sheet for skin 考司美德制药株式会社 2022-11-25 CN disclosed
US-20220233833-A1 FAST-DISSOLVING MICRONEEDLE COSMED PHARMACEUTICAL CO., LTD. (JP) 2022-07-28 US disclosed
CN-113766913-A Short time dissolving microneedle 考司美德制药株式会社 2021-12-07 CN disclosed
US-9442399-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus and phthalocyanine crystal CANON KABUSHIKI KAISHA (JP) 2016-09-13 US disclosed
US-9442399-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus and phthalocyanine crystal CANON KABUSHIKI KAISHA (JP) 2016-09-13 US disclosed
EP-2498746-B1 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES UNILEVER PLC NO 41424 (GB) 2016-08-24 EP disclosed
EP-2743772-B1 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus and phthalocyanine crystal CANON KK (JP) 2016-04-20 EP disclosed
EP-2116224-B1 COSMETIC COMPOSITION JNC CORP (JP) 2016-01-27 EP disclosed
US-20140170542-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS AND PHTHALOCYANINE CRYSTAL CANON KABUSHIKI KAISHA (JP) 2014-06-19 US disclosed
US-20140170542-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS AND PHTHALOCYANINE CRYSTAL CANON KABUSHIKI KAISHA (JP) 2014-06-19 US disclosed
EP-2743772-A1 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus and phthalocyanine crystal Canon Kabushiki Kaisha (JP) 2014-06-18 EP disclosed
US-20100055060-A1 COSMETIC COMPOSITION JNC CORPORATION (JP) 2010-03-04 US disclosed
EP-2116224-A1 COSMETIC COMPOSITION Chisso Corporation (JP) 2009-11-11 EP disclosed
EP-1604647-B1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof CHISSO CORP (JP) 2008-05-07 EP disclosed
US-20060246099-A1 Compositions containing piperazine compounds L'OREAL (FR) 2006-11-02 US disclosed
EP-1714639-A1 Cosmetic compositions containing piperazine derivatives L'OREAL (FR) 2006-10-25 EP disclosed
EP-1714639-A1 Cosmetic compositions containing piperazine derivatives L'OREAL (FR) 2006-10-25 EP disclosed
US-20060018867-A1 Cosmetic composition and production thereof ICHIMARU PHARCOS CO., LTD 2006-01-26 US disclosed
EP-1604647-A1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof Ichimaru Pharcos Co., Ltd. (JP) 2005-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018867-A1 Cosmetic composition and production thereof CUTA, PARG, TYR SIGMAR1 222/4885CCR3 4352/4885POLB 27/4885
US-20060246099-A1 Compositions containing piperazine compounds KLF5, CUTA, COL2A1 SIGMAR1 4633/4885CCR3 4456/4885POLB 749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.