Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695202 | 0.81 | TP53 (0.60) | FAAHS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9308211 | 0.81 | FAAH (0.63) | FAAHS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL28827967 | 0.80 | FAAH (0.65) | FAAHS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL5222701 | 0.76 | FAAH (0.63) | FAAHSMN1; SMN2LMNA | |
| SCHEMBL14111813 | 0.76 | EPHX2 (0.58) | FAAHSMN1; SMN2LMNA | |
| SCHEMBL9307359 | 0.75 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNATP53TSHR | |
| SCHEMBL9565606 | 0.74 | FAAH (0.73) | FAAH | |
| SCHEMBL7507343 | 0.74 | TP53 (0.59) | LMNATP53TSHR | |
| SCHEMBL8953576 | 0.74 | TP53 (0.59) | LMNATP53TSHR | |
| SCHEMBL3031391 | 0.74 | S1PR2 (0.49) | S1PR2S1PR1S1PR3LPAR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |