Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819733 | 0.95 | HTR2A (0.57) | MAOAHTR2AHRH1CYP19A1CYP2A6 | |
| SCHEMBL11187960 | 0.87 | MAOA (0.59) | MAOAHTR2AHRH1CYP2A6SMN1; SMN2 | |
| SCHEMBL8466491 | 0.87 | HRH1 (0.54) | MAOAHTR2AHRH1CYP19A1CYP2A6 | |
| SCHEMBL15776714 | 0.85 | HRH1 (0.57) | MAOAHTR2AHRH1TAAR1 | |
| SCHEMBL1538332 | 0.84 | CYP19A1 (0.54) | HTR2ACYP19A1CYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL9819796 | 0.84 | ALDH1A1 (0.55) | MAOAHTR2AHRH1CYP19A1 | |
| SCHEMBL10014098 | 0.82 | HTR2A (0.49) | HTR2ACYP19A1SIGMAR1KCNH2 | |
| SCHEMBL15286352 | 0.81 | GABBR2 (0.50) | MAOAHTR2AHRH1CYP19A1CYP2A6 | |
| SCHEMBL2093783 | 0.80 | CYP19A1 (0.49) | CYP19A1SIGMAR1ACP3KCNH2 | |
| SCHEMBL2093779 | 0.80 | CYP19A1 (0.49) | CYP19A1SIGMAR1ACP3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |