Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295721 | 0.81 | MCL1 (0.40) | MCL1FAAHCETPMAOBELANE | |
| SCHEMBL9819945 | 0.80 | MEN1 (0.41) | ELANEALDH1A1KDM4EPOLBPKM | |
| SCHEMBL9819998 | 0.76 | GAA (0.44) | MAOBALDH1A1MAPK1KDM4EPOLB | |
| SCHEMBL9836825 | 0.75 | AKR1B1 (0.39) | CETPALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL9835193 | 0.71 | GAA (0.45) | ELANEALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL9820046 | 0.71 | GRIN1 (0.36) | MCL1CETPALDH1A1KDM4EPOLB | |
| SCHEMBL9819961 | 0.71 | GAA (0.43) | CETPALDH1A1MAPK1KDM4EPOLB | |
| SCHEMBL10351910 | 0.66 | RAB9A (0.34) | ELANEALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL9819887 | 0.66 | MAPT (0.41) | ELANEALDH1A1MAPK1KDM4EPOLB | |
| SCHEMBL28681416 | 0.65 | KDM4E (0.39) | MAOBELANEALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210559-B1 | N-ACYLDIHYDRORESORUFIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AS WELL AS THEIR USE FOR THE DETERMINATION OF HYDROGEN PEROXIDE, PEROXIDATICALLY ACTIVE COMPOUNDS, OR PEROXIDASE | Roche Diagnostics GmbH (DE) | 1991-09-25 | — | — | EP | disclosed |
| EP-0156347-B1 | GLYCOSIDES OF RESOFURIN DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE IN THE DETERMINATION OF THE ACTIVITY OF GLYCOSIDASES | Roche Diagnostics GmbH (DE) | 1991-09-04 | — | — | EP | disclosed |
| EP-0210559-A2 | N-Acyldihydroresorufin derivatives, process for their preparation as well as their use for the determination of hydrogen peroxide, peroxidatically active compounds, or peroxidase | Roche Diagnostics GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |